Biomedical Engineering


Yong Du, M.D., Ph.D.
Research Assistant Professor
Office Location: SERC 2010
Phone: 832-842-8855
Fax: 713-743-0226
Email: ydu9 [at] central [dot] uh [dot] edu

Dr. Du received his Ph.D in Internal Medicine /Nephrology at Sun Yat-sen University, China in 2004. He completed his postdoctoral training in Internal Medicine /Rheumatology at UT Southwestern Medical Center.


Ph.D., Internal Medicine /Nephrology, Sun Yat-sen University (China)

Selected Publications: 

Li Y, Raman I, Du Y, Yan M, Min S, Yang J, Fang X, Li W, Lu J, Zhou XJ, Mohan C, Li QZ. Kallikrein transduced mesenchymal stem cells protect against anti-GBM disease and lupus nephritis by ameliorating inflammation and oxidative stress. PLoS One. 2013;8(7):e67790.

Min SY, Yan M, Du Y, Wu T, Khobahy E, Kwon SR, Taneja V, Bashmakov A, Nukala S, Ye Y, Orme J, Sajitharan D, Kim HY, Mohan C. Intra-articular nuclear factor-κBblockade ameliorates collagen-induced arthritis in mice by eliciting regulatory T cells and macrophages. Clin Exp Immunol. 2013; 172(2):217-27.

Hao G, Du Y, Zhou XJ, Guo J, Sun X, Mohan C, Oz OK. Serial non-invasive assessment of antibody induced nephritis in mice using positron emission tomography. PLoS One. 2013; 8(2):e57418. (Joint first authors.)

Xie C, Du Y, Kumar K, Li L, Han J, Liu K, Zhou XJ, Mohan C. Lupus-prone strains vary in susceptibility to antibody-mediated end organ disease. Genes Immun. 2013;14(3):170-8.

Wu T, Du Y, Han J, Singh S, Xie C, Guo Y, Zhou XJ, Ahn C, Saxena R, Mohan C. Urinary angiostatin--a novel putative marker of renal pathology chronicity in lupus nephritis. Mol Cell Proteomics. 2013;12(5):1170-9.

Shao X, Yang R, Yan M, Li Y, Du Y, Raman I, Zhang B, Wakeland EK, Igarashi P, Mohan C, Li QZ. Inducible expression of kallikrein in renal tubular cells protects mice against spontaneous lupus nephritis. Arthritis Rheum. 2013;65(3):780-91.

Ozaltin F, Li B, Rauhauser A, An SW, Soylemezoglu O, Gonul II, Taskiran EZ, Ibsirlioglu T, Korkmaz E, Bilginer Y, Duzova A, Ozen S, Topaloglu R, Besbas N, Ashraf S, Du Y, Liang C, Chen P, Lu D, Vadnagara K, Arbuckle S, Lewis D, Wakeland B, Quigg RJ, Ransom RF, Wakeland EK, Topham MK, Bazan NG, Mohan C, Hildebrandt F, Bakkaloglu A, Huang CL, Attanasio M. DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN. J Am Soc Nephrol. 2013;24(3):377-84.

Du Y, An S, Liu L, Li L, Zhou XJ, Mason RP, Mohan C. Serial non-invasive monitoring of renal disease following immune-mediated injury using near-infrared optical imaging. PLoS One. 2012;7(9):e43941.

Li L, Nukala S, Du Y, Han J, Liu K, Hutcheson J, Pathak S, Li Q, Mohan C. Murine lupus strains differentially model unique facets of human lupus serology. Clin Exp Immunol. 2012;168(2):178-85.

Min SY, Fu Y, Hutcheson J, Wu T, Khobahy E, Zhu J, Vanarsa K, Du Y, Park MJ, Park HS, Saxena R, Kim HY, Mohan C. Peritoneal catheter implantation elicits IL-10-producing immune-suppressor macrophages through a MyD88-dependent pathway. Clin Immunol. 2012; 143(1):59-72.

Hu Y, Liang H, Du Y, Zhu Y, Wang X. Curcumin inhibits transforming growth factor-beta activity via inhibition of Smad signaling in HK-2 cells. Am J Nephrol. 2010; 31(4):332-41.

Du Y, Fu Y, Mohan C. Experimental anti-GBM nephritis as an analytical tool for studying spontaneous lupus nephritis. Arch Immunol Ther Exp (Warsz). 2008; 56(1):31-40. Review.

Xie C, Rahman ZS, Xie S, Zhu J, Du Y, Qin X, Zhou H, Zhou XJ, Mohan C. Strain distribution pattern of immune nephritis--a follow-up study. Int Immunol. 2008; (6):719-28.

Fu Y, Du Y, Mohan C. Experimental anti-GBM disease as a tool for studying spontaneous lupus nephritis. Clin Immunol. 2007; 124(2):109-18. Review.

Yong D, Qing WQ, Hua L, Kan JJ, Xi CJ, Jin QQ, Chao SH. Association of angiotensin I-converting enzyme gene insertion/deletion polymorphism and IgA nephropathy: a meta-analysis. Am J Nephrol. 2006; 26(5):511-8. (Corresponding author)

Yong D, QingQing W, Hua L, Yang LX, QingLing Z, Ying H, QiaoJing Q, HanChao S. Association of uteroglobin 38A polymorphism with IgA nephropathy: a meta-analysis. 1. Am J Kidney Dis. 2006; 48(1):1-7. (Corresponding author)

Xia Y, Li Y, Du Y, Yang N, Li C, Leung JC, Lam MF, Huang W, Chen S, Maxwell PH, Lai KN, Wang Y. Association of MEGSIN 2093C-2180T haplotype at the 3' untranslated region with disease severity and progression of IgA nephropathy. Nephrol Dial Transplant. 2006; 21(6):1570-4.

Wu Q, Du Y, Yang N, Liang Y, Li Y. Microvasculature change and placenta growth factor expression in the early stage of a rat remnant kidney model. Am J Nephrol.2006; 26(1):97-104.

Yang NS, Wu QQ, Du Y, Zhang R, Li YJ, Ye RG, Yu XQ. [Risk factors affecting the long-term outcome of IgA nephropathy]. Zhonghua Nei Ke Za Zhi. 2005; 44(8):597-600.

Chen S, Song C, Guo H, Xu P, Huang W, Zhou Y, Sun J, Li CX, Du Y, Li X, Liu Z, Geng D, Maxwell PH, Zhang C, Wang Y. Distinct novel mutations affecting the same base in the NIPA1 gene cause autosomal dominant hereditary spastic paraplegia in two Chinese families. Hum Mutat. 2005;25(2):135-41.

Li YJ, Du Y, Li CX, Guo H, Leung JC, Lam MF, Yang N, Huang F, Chen Y, Fang JQ, Maxwell PH, Lai KN, Wang Y. Family-based association study showing that immunoglobulin A nephropathy is associated with the polymorphisms 2093C and 2180T in the 3' untranslated region of the Megsin gene. J Am Soc Nephrol. 2004;15(7):1739-43.