Functional Imaging of Embryonic Development with Noninvasive Volumetric Optoacoustic Tomography

Maryam Hatami, Ph.D.
Optoacoustic (OA) tomography is a real-time, noninvasive imaging method combining pulsed
laser excitation and ultrasonic detection of the tissue response. The experimental setup is
composed of an optical source for illumination/excitation, the ultrasound detection array, and
the computing system for data acquisition and image reconstruction. OA tomography is a rapidly
emerging imaging modality that is suitable for live embryonic imaging as it enables high-contrast
imaging combined with high spatial resolution and has demonstrated an exclusive potential for
noninvasive deep tissue visualization. I present some of our recent work using OA tomography
for in vivo volumetric visualization of murine embryonic development.